PTM Analysis

Unprecedented insight into your samples.

Post-translational modifications, or PTMs, are physical alterations that occur in a regulated manner to almost every protein after the initial translation.

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Why study PTMs?

While the function of some PTMs is still unknown, scientists now understand that most of these modifications are implicated in the regulation of a plethora of biological processes such as cell survival, energy metabolism, and signal transduction, just to name a few. Mechanistically, PTMs are the way cells detect modifications in their environment, convey a signal to the appropriate organelle, and produce an adapted biological response to the stimulus.

PTMs are very broad in nature and can be reversible or irreversible. According to their impact on the target protein, PTMs can also be categorized into five distinct families.