Quality control of tryptic digestion


The DIGESTIF standard consists of a soluble recombinant protein scaffold to which a set of 11 artificial peptides (iRT peptides) with good ionization properties has been incorporated. In the protein scaffold, the amino acids flanking iRT peptide cleavage sites were selected to either favor or hinder protease cleavage. After sample processing, the retention time and relative intensity pattern of the released iRT peptides can be used to assess the quality of sample workup, the extent of digestion and the performance of the LC-MS system.

This product is for research use only and is not intended for diagnostic or therapeutic use.

Specific labeling:

Arginine: 13C6 15N4  >99%

Lysine: 13C6 15N2 >99%

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*PhenoSwitch Bioscience distributes Promise Proteomics products exclusively in Canada and the USA. If you are not located in these regions, please visit the Promise Proteomics website for more information.