The highly-specific capture of phosphorylated peptides from complex protein digests pose a significant challenge to proteomics researchers. Several technologies with varying degrees of specificity and affinity have been developed to enrich phosphopeptides. These different technologies can be used either alone or in combination to increase coverage of the phosphoproteome. MagReSyn® ZrO2 microparticles allow highly specific, reproducible enrichment of phosphopeptides from complex biological samples such as protein digests. MagReSyn® ZrO2 microparticles may be used alone or in combination with MagReSyn® TiO2, MagReSyn® Zr-IMAC and/or MagReSyn® Ti-IMAC microparticles to enrich diverse types of phosphopeptides for comprehensive phosphoproteomics analyses.
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