MagResyn Zr-IMAC

Magnetic microparticles with chelated Zr⁴⁺ metal ions for highly-specific phosphopeptide enrichment

Protein phosphorylation is one of the most important post-translational modifications and is a critical process in cellular signaling and regulation of cellular networks. Comprehensive analysis of the phosphoproteome is a challenging task due to the transient and sub-stoichiometric nature of phosphorylation sites. High-throughput phosphoproteome analysis by mass spectrometry requires compatible technologies than can specifically enrich phosphopeptides. MagReSyn® Zr-IMAC microparticles have a flexible linker (to reduce steric hindrance) activated with phosphonate groups for Zr4+ chelation. The unique properties of the proprietary ReSyn microparticle technology allows extremely specific, reproducible enrichment of phosphopeptides from complex biological samples/protein digests. The microparticles can be used either alone, or in combination with MagReSyn® Ti-IMAC, MagReSyn® TiO2 and/or MagReSyn® ZrO2 to increase phosphoproteome coverage. Products for phosphopeptide enrichment are validated for the intended application using our stringent QC procedures. 

This product is available in Standard or High Performance.

• Support: Proprietary polymer microparticles containing iron oxide (magnetite)
• Bead size: ~5-10 µm
• Formulation: 20 mg.ml-1 suspension in 20% ethanol

*PhenoSwitch Bioscience only distributes MagResyn products in Canada. If you are not located in Canada, please visit the MagResyn website for more information.