MagReSyn Protein G

High capacity Protein G for affinity purification of antibodies and immunoprecipitation

MagReSyn^® Protein G is a proprietary magnetic polymeric microparticle support that provides a simple and convenient method for highly specific capture of various immunoglobulins from biological samples. Recombinant Streptococcal Protein G (lacking the albumin binding region for increased immunoglobulin specificity) is covalently linked to the magnetic microparticles reducing leaching during your experimentation, and potentially stabilizing the Protein G for applications in non-standard conditions. Protein G binds to most mammalian immunoglobulins with greater affinity than Protein A, including human IgG3 and rat IgG2a. It does not react with human IgM, IgD or IgA.

The high recombinant Protein G content of MagReSyn^® ensures a high immunoglobulin capacity allowing for experimental miniaturization. MagReSyn^® Protein G microparticles have been engineered to be highly specific, providing single step purification of IgG to >95% from whole serum samples.

• Support: Proprietary polymer microparticles containing iron oxide (magnetite) with immobilized Protein G
• Binding capacity: > 2.4 mg.ml^-1 (Rabbit IgG)
• Bead size: ~5-10 µm
• Formulation: 15 mg.ml^-1 suspension in Tris buffer